CrestOptics Launches CICERO System to Provide All-in-One Solution for Widefield and Spinning Disk Confocal Microscopy


CrestOptics SpA, a manufacturer of high-end microscope solutions and advanced systems for fluorescence microscopy and diagnostic applications, today announced the launch of its new rotating disk confocal microscope system, CICERO. Focusing on the essential elements of epi-fluorescence and confocal microscopy, CICERO has been developed to make high-end imaging accessible to the wider scientific community by providing a compact and cost-effective system for powerful imaging solutions.

CICERO CrestOptics spinning disc. Image Credit: CrestOptics SpA

​​​​​​​The CICERO CrestOptics system is an all-in-one solution for widefield and confocal imaging. Building on the recent success of the Enterprise DeepSIM module as one of ‘Microscopy Today’The 10 Best Microscopy Innovations for 2022′, CICERO has been developed to expand the Company’s portfolio and enable accessible fluorescence imaging in one compact, budget-friendly, yet high-performance solution. Rotating disk confocal instruments can be easily integrated into existing workflows, with maximum configuration flexibility to support smooth transitions and ease of use, enabling a wide range of imaging applications across basic and applied research.

The compact system facilitates a simplified transition between widefield and confocal imaging, allowing users to easily switch between modes as their imaging needs evolve. The widefield mode supports the collection of informative data from samples, such as monolayer cells and tissue sections, while the confocal mode enables high-quality analysis of larger 3D structures, including organoids or whole organisms. Additionally, CICERO’s speed and light efficiency provide capabilities for prolonged live imaging and capture of fast cellular events, such as chromosome segregation and organelle trafficking.

Alessandra Scarpellini, Chief Commercial Officer, CrestOptics, said “Studying the market, we realized that there was a need for an instrument that was equally powerful and easily integrated into different platforms. Our team has worked hard to ensure that CICERO maintains the level of technological and performance excellence that CrestOptics provides in its existing portfolio, while ensuring that the instruments are compact and cost-effective..” He added: “Our system is designed to support and advance scientific research – in Italian, Cicero is someone who guides individuals through journeys to see the most interesting things. True to our values, we envision our CICERO system doing just that, guiding researchers from the start of their confocal journey and supporting them in more meaningful discoveries..”

The CICERO CrestOptics system will be launched in Focus on Microscopy (FOM) 20232t– 5th April, in Porto, Portugal, including a live demonstration of the system at Booth 38/39.

For more information on the CICERO system, please visit



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