Biotechnology

Particulate matter associated with improving hospital procedures in heart failure

[ad_1]

Long-term exposure to fine particulate air pollution is associated with increased hospital procedures in heart failure patients, according to a study published May 3, 2023, in an open access journal. PLOS ONE by Samantha Catalano of the University of North Carolina at Chapel Hill, USA, and colleagues.

Credit: Samantha Catalano, CC-BY 4.0 (https://creativecommons.org/licenses/by/4.0/)

Long-term exposure to fine particulate air pollution is associated with increased hospital procedures in heart failure patients, according to a study published May 3, 2023, in an open access journal. PLOS ONE by Samantha Catalano of the University of North Carolina at Chapel Hill, USA, and colleagues.

Small particles in the air smaller than 2.5μm in diameter (PM2.5) are air pollutants generated by traffic, industrial activities, combustion, and others. Although PM2.5 exposure has been associated with illness and death worldwide, few studies have quantified this association using hospital procedures. In this study, the authors analyzed the effect of long-term exposure to PM2.5 on hospital procedures in heart failure patients.

Researchers examined electronic health records for 20,920 patients diagnosed with heart failure, 15,979 of whom subsequently received at least one of 53 common procedures (>10% frequency) in the University of North Carolina Health System from 2004-2016. Researchers used each patient’s address in addition to the date of their heart failure diagnosis to map and analyze environmental exposure data alongside their health records.

The analysis revealed that three specific procedures were significantly more likely to be performed in patients with increased PM2.5 exposure: stress test (6.84% increase per 1 μg/m3 increase in PM2.5), glycosylated hemoglobin test, which screens for diabetes (10.8 % increased), and the prothrombin time test, which evaluates blood clotting (15.8% increase). The prothrombin time test remained significantly associated with this exposure even after adjusting for access to health care and healthy food by region.

As these three tests relate to diagnostic tests for cardiorespiratory health, the authors argue that their results provide evidence that patients with high PM2.5 exposure experience more cardiovascular morbidity, prompting healthcare professionals to perform more diagnostic tests.

The health records on which this study was based did not include individual-level socioeconomic data, or data about procedures that may have been performed outside the University of North Carolina Health System (unless those records were transferred). Nonetheless, these results will assist future researchers in better estimating the burden of PM2.5 exposure in patients and hospital systems.

The authors add: “The relationship between PM2.5 and hospital procedures can provide us with unique insights into the impact of PM2.5 exposure on patients and healthcare systems. We observed an increase in the performance of diagnostic procedures with increased PM2.5 exposure, which is in agreement with the known mechanisms of PM2.5 exposure. This research provides evidence that hospital procedures can be a unique lens through which to view the health impacts of exposure to air pollution.”

#####

In your coverage, please use this URL to provide access to articles freely available at PLOS ONE: https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0283759

Quote: Catalano S, Moyer J, Weaver A, Di Q, Schwartz JD, Catalano M, et al. (2023) Relationship between long-term exposure to fine particulate matter and hospital procedures in heart failure patients. PLoS ONE 18(4): e0283759. https://doi.org/10.1371/journal.pone.0283759

Author Country: US, China

Funding: This work was supported by Harvard participants, grant RD-835872-01 from the US Environmental Protection Agency and grant UL1TR002489 from the National Center for Advancing the Science of Translation, National Institutes of Health (NIH). Funders had no role in study design, data collection and analysis, decision to publish, or manuscript preparation.


[ad_2]

Source link

Related Articles

Back to top button