Carbon Based Responsive Nanomaterials

Because of their versatility, including their use in disease detection and treatment, carbon-based stimulus-responsive nanomaterials are attracting much interest. They function in response to extrinsic (temperature, light, magnetic fields, ultrasound), as well as endogenous stimuli (pH, temperature, enzymes, and redox).

Classification, application, summary, and views of carbon-based stimulus-responsive nanomaterials. Image Credit: Cyborg Systems and Bionics

As smart materials with physicochemical characteristics that can be adjusted dynamically in reaction to changes in internal or external environmental stimuli, carbon-based stimulus-responsive nanomaterials can be used.

They provide new possibilities for manufacturing state-of-the-art smart nanomaterials due to the diversity of nanostructures and molecular designs incorporated, as well as functional complexes with multiple carriers.

Based on its microstructure and physical characteristics, the research team from Beijing Institute of Technology reviewed the classification and use of carbon-based stimulus-responsive nanomaterials.

They also discuss the use of these materials in bioimaging, tumor therapy, and other fields. Finally, they discussed the advantages and disadvantages of carbon-based excitation-responsive nanomaterials, summarized them, and predicted future prospects for their application.

Their recommendations are published in Cyborg Systems and Bionics on March 9thth2023.

Carbon nanotubes, carbon nanospheres and carbon nanofibers are the three main groups into which the authors divided carbon-based nanomaterials.

Several carbon-based stimulus-responsive nanomaterials used in scientific research and advanced engineering are listed at the same time, and more nuanced variations are seen in different synthesis and preparation techniques of carbon nanomaterials.

Applications of carbon-based stimulus-responsive materials in the fields of probe, bioimaging, and tumor treatment are then listed by the authors. Due to their distinctive optical characteristics, carbon-based nanomaterials are used in optical imaging and anti-counterfeiting applications.

The sensitivity of carbon-based nanomaterials can be increased by conjugation with various specific detection reagents. In addition, carbon-based nanomaterials can be utilized as therapeutic agents (photothermal, photodynamic, chemotherapeutic, etc.) or drug delivery systems for disease treatment.

Finally, the authors explore the future views and constraints of developing carbon-based stimulus-responsive materials. As well as possessing outstanding physical and chemical characteristics, carbon-based excitability responsive materials can be functionalized by combining them with other polymers, making them effective drug delivery and cancer treatment carriers.

Because significant data from clinical trials in medical treatments is currently lacking, it is uncertain how safely the material responds to carbon-based stimuli. Research on toxicity, pathology, and biodynamics must be carried out in depth to defuse the debate around carbon-based stimulus-responsive materials and improve reliability.

This study examines the current weaknesses and potential improvements for carbon-based stimulus-responsive materials, and also discusses how they are classified and used in biology and chemistry. In general, many studies have demonstrated that the hybridization of carbon-based stimulus-responsive materials plays an important role in the biomedical field.

However, it is very important to carry out in-depth studies of toxicology and pathology in order to better reduce the disputes around them and increase their credibility. Future research is anticipated to improve the safety of carbon-based stimulus-responsive materials and make them more beneficial to human life by creating new synthetic methods or composite materials.

Journal Reference

Zhao, C., et al. (2023) Carbon-Based Responsive Nanomaterials: Classification and Applications. Cyborg Systems and Bionics. doi:10.34133/cbsystems.0022


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